Th\u00f4ng th\u01b0\u1eddng ph\u1ea3i \u0111\u1ebfn th\u00e1ng 10 c\u00e1c gi\u1ea3i Nobel m\u1edbi \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1. Tuy nhi\u00ean, t\u1eeb cu\u1ed1i n\u0103m qua \u0111\u00e3 c\u00f3 kh\u00f4ng \u00edt \u0111\u1ed3n \u0111o\u00e1n r\u1eb1ng gi\u1ea3i Nobel Y h\u1ecdc n\u0103m nay s\u1ebd trao cho ng\u01b0\u1eddi c\u00f3 c\u00f4ng t\u00ecm ra artemisinin, lo\u1ea1i thu\u1ed1c ch\u1eefa s\u1ed1t r\u00e9t \u0111\u00e3 c\u1ee9u h\u00e0ng tri\u1ec7u ng\u01b0\u1eddi kh\u1eafp th\u1ebf gi\u1edbi. S\u1ef1 ra \u0111\u1eddi c\u1ee7a lo\u1ea1i thu\u1ed1c n\u00e0y t\u1eeb ng\u00e0y \u0111\u1ea7u ti\u00ean cho \u0111\u1ebfn khi \u0111\u01b0\u1ee3c th\u1ebf gi\u1edbi c\u00f4ng nh\u1eadn l\u00e0 m\u1ed9t c\u00e2u chuy\u1ec7n ly k\u1ef3, v\u00ec b\u1eaft ngu\u1ed3n t\u1eeb cu\u1ed9c chi\u1ebfn ch\u1ed1ng M\u1ef9 c\u1ee7a Vi\u1ec7t Nam v\u00e0 c\u00f3 s\u1ef1 \u0111\u00f3ng g\u00f3p c\u1ee7a gi\u1edbi khoa h\u1ecdc n\u01b0\u1edbc ta. Nh\u00e2n ng\u00e0y S\u1ed1t r\u00e9t th\u1ebf gi\u1edbi (25.4), xin \u0111i\u1ec3m l\u1ea1i s\u1ef1 ki\u1ec7n y khoa n\u00e0y b\u1eb1ng lo\u1ea1t b\u00e0i sau.<\/p>\n

B\u00c0I 1: D\u1ef1 \u00e1n tuy\u1ec7t m\u1eadt 523<\/h2>\n
SGTT.VN – Trong th\u1ebf k\u1ef7 21, s\u1ed1t r\u00e9t d\u01b0\u1eddng nh\u01b0 b\u1ecb che khu\u1ea5t b\u1edfi nh\u1eefng d\u1ecbch b\u1ec7nh th\u1eddi th\u01b0\u1ee3ng nh\u01b0 AIDS, SARS, c\u00fam A\/H5N1, c\u00fam A\/H1N1, nh\u01b0ng n\u1ebfu bi\u1ebft r\u1eb1ng cho \u0111\u1ebfn nay m\u1ed7i n\u0103m c\u00f3 kho\u1ea3ng 250 tri\u1ec7u ng\u01b0\u1eddi kh\u1eafp th\u1ebf gi\u1edbi m\u1eafc b\u1ec7nh v\u00e0 h\u01a1n 1 tri\u1ec7u ng\u01b0\u1eddi ch\u1ebft v\u00ec s\u1ed1t r\u00e9t, th\u00ec b\u1ea5t k\u1ef3 ai c\u0169ng ph\u1ea3i gi\u1eadt m\u00ecnh.<\/p>\n\n\n\n\n
$\"thanhhao\"$ <\/td>\n<\/tr>\n
Thanh hao hoa v\u00e0ng, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 thanh cao hoa v\u00e0ng, thanh hao, thanh cao, th\u1ea3o cao, ng\u1ea3i si, ng\u1ea3i h\u00f4i, ng\u1ea3i \u0111\u1eafng… \u1ea2nh: TL<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Theo nhi\u1ec1u t\u00e0i li\u1ec7u, trong cu\u1ed9c chi\u1ebfn ch\u1ed1ng M\u1ef9 nh\u1eefng n\u0103m 60 th\u1ebf k\u1ef7 20, b\u1ed9 \u0111\u1ed9i Vi\u1ec7t Nam b\u1ecb s\u1ed1t r\u00e9t t\u1ea5n c\u00f4ng r\u1ea5t d\u1eef d\u1ed9i. GS Zhou Yiqing, nh\u00e0 khoa h\u1ecdc Trung Qu\u1ed1c t\u1eebng sang Vi\u1ec7t Nam th\u1eddi \u0111\u00f3 \u0111\u1ec3 nghi\u00ean c\u1ee9u v\u1ec1 s\u1ed1t r\u00e9t, h\u1ed3i t\u01b0\u1edfng: \u201cD\u1ecdc \u0111\u01b0\u1eddng m\u00f2n H\u1ed3 Ch\u00ed Minh l\u00e0 nh\u1eefng tr\u1eadn m\u01b0a bom d\u1eef d\u1ed9i c\u1ee7a l\u1ef1c l\u01b0\u1ee3ng Hoa K\u1ef3 \u0111\u1ed5 xu\u1ed1ng v\u00e0 t\u00f4i \u0111\u00e3 ch\u1ee9ng ki\u1ebfn s\u1ed1t r\u00e9t l\u00e0m ti\u00eau hao m\u1ed9t n\u1eeda s\u1ee9c m\u1ea1nh chi\u1ebfn \u0111\u1ea5u c\u1ee7a b\u1ed9 \u0111\u1ed9i Vi\u1ec7t Nam, th\u1eadm ch\u00ed gi\u1ea3m \u0111\u1ebfn 90% s\u1ee9c m\u1ea1nh m\u1ed9t khi binh l\u00ednh b\u1ecb l\u00ean c\u01a1n s\u1ed1t r\u00e9t. Khi \u0111\u00f3, ngo\u00e0i chi\u1ebfn tr\u01b0\u1eddng b\u1ed9 \u0111\u1ed9i th\u01b0\u1eddng n\u00f3i: \u201cCh\u00fang t\u00f4i kh\u00f4ng s\u1ee3 \u0111\u1ebf qu\u1ed1c M\u1ef9 m\u00e0 ch\u1ec9 s\u1ee3 b\u1ec7nh s\u1ed1t r\u00e9t\u201d, cho d\u00f9 s\u1ef1 th\u1eadt l\u00e0 c\u0103n b\u1ec7nh n\u00e0y g\u00e2y thi\u1ec7t h\u1ea1i cho c\u1ea3 hai b\u00ean\u201d. S\u1ed1t r\u00e9t kh\u1ee7ng khi\u1ebfp nh\u01b0 th\u1ebf v\u00ec theo gi\u1edbi y h\u1ecdc, k\u00fd sinh tr\u00f9ng s\u1ed1t r\u00e9t \u0111\u00e3 kh\u00e1ng v\u1edbi chloroquine, lo\u1ea1i thu\u1ed1c ch\u1eefa s\u1ed1t r\u00e9t ph\u1ed5 bi\u1ebfn th\u1eddi \u0111\u00f3.<\/p>\n
Tr\u01b0\u1edbc t\u00ecnh h\u00ecnh n\u00e0y, Ch\u00ednh ph\u1ee7 Vi\u1ec7t Nam D\u00e2n ch\u1ee7 C\u1ed9ng ho\u00e0 \u0111\u00e3 nh\u1edd Trung Qu\u1ed1c nghi\u00ean c\u1ee9u t\u00ecm ra m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1eefa s\u1ed1t r\u00e9t h\u1eefu hi\u1ec7u. Trong m\u1ed9t b\u00e0i vi\u1ebft \u0111\u0103ng tr\u00ean t\u1ea1p ch\u00ed Cell n\u0103m qua, hai t\u00e1c gi\u1ea3 Louis H. Miller v\u00e0 Xinzhuan Su c\u1ee7a vi\u1ec7n D\u1ecb \u1ee9ng v\u00e0 b\u1ec7nh nhi\u1ec5m tr\u00f9ng qu\u1ed1c gia Hoa K\u1ef3, vi\u1ebft: \u201cCh\u00ednh ph\u1ee7 Trung Qu\u1ed1c \u0111\u00e3 h\u1ecdp t\u1ea1i B\u1eafc Kinh ng\u00e0y 23.5.1967 \u0111\u1ec3 t\u00ecm ki\u1ebfm m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1eefa s\u1ed1t r\u00e9t h\u1eefu hi\u1ec7u. K\u1ebft qu\u1ea3 l\u00e0 m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u s\u1ed1t r\u00e9t tuy\u1ec7t m\u1eadt c\u1ea5p qu\u1ed1c gia ra \u0111\u1eddi, g\u1ecdi l\u00e0 D\u1ef1 \u00e1n 523, quy t\u1ee5 h\u01a1n 500 nh\u00e0 khoa h\u1ecdc thu\u1ed9c 60 ph\u00f2ng th\u00ed nghi\u1ec7m kh\u00e1c nhau\u201d.<\/p>\n
L\u00e0 m\u1ed9t th\u00e0nh vi\u00ean trong nh\u00f3m nghi\u00ean c\u1ee9u, GS Zhou Yiqing n\u00f3i: \u201cCh\u00fang t\u00f4i \u0111\u01b0\u1ee3c chia th\u00e0nh hai nh\u00f3m, m\u1ed9t nh\u00f3m theo \u0111u\u1ed5i ch\u1ebf t\u1ea1o thu\u1ed1c t\u1eeb c\u00e1c ch\u1ea5t ho\u00e1 h\u1ecdc, m\u1ed9t nh\u00f3m \u0111i v\u00e0o h\u01b0\u1edbng y h\u1ecdc c\u1ed5 truy\u1ec1n. Trong nh\u00f3m sau, c\u00e1c chuy\u00ean gia xem x\u00e9t m\u1ed9t lo\u1ea1t nh\u1eefng c\u00e2y c\u1ecf \u0111\u01b0\u1ee3c l\u01b0u truy\u1ec1n trong d\u00e2n gian ho\u1eb7c ghi ch\u00e9p trong y v\u0103n c\u1ed5 c\u00f3 t\u00e1c d\u1ee5ng ch\u1eefa s\u1ed1t r\u00e9t. Ch\u00fang t\u00f4i chia nhau \u0111\u1ebfn t\u1eadn c\u00e1c l\u00e0ng b\u1ea3n xa x\u00f4i \u0111\u1ec3 h\u1ecfi ng\u01b0\u1eddi d\u00e2n v\u1ec1 nh\u1eefng b\u00e0i thu\u1ed1c b\u00ed m\u1eadt ch\u1eefa s\u1ed1t b\u1eb1ng th\u1ea3o d\u01b0\u1ee3c. Cu\u1ed1i c\u00f9ng c\u00e2y thanh hao hoa v\u00e0ng (t\u00ean Latinh l\u00e0 Artemisia annua) \u0111\u01b0\u1ee3c \u201cch\u1ecdn m\u1eb7t g\u1eedi v\u00e0ng\u201d \u0111\u1ec3 t\u1eadp trung nghi\u00ean c\u1ee9u s\u00e2u h\u01a1n\u201d.<\/p>\n
Ra \u0111\u1eddi trong v\u1ea5t v\u1ea3 v\u00e0 tranh c\u00e3i<\/h2>\n
T\u00e1c d\u1ee5ng c\u1eaft s\u1ed1t c\u1ee7a thanh hao hoa v\u00e0ng \u0111\u01b0\u1ee3c ghi nh\u1eadn trong nh\u1eefng c\u1ed5 m\u1ed9 th\u1eddi H\u00e1n v\u00e0 \u0111\u01b0\u1ee3c d\u00e2n gian n\u01b0\u1edbc n\u00e0y c\u00f4ng nh\u1eadn qua nhi\u1ec1u th\u1ebf k\u1ef7. N\u0103m 340, l\u1ea7n \u0111\u1ea7u ti\u00ean c\u00e2y thu\u1ed1c n\u00e0y \u0111\u01b0\u1ee3c C\u00e1t H\u1ed3ng, m\u1ed9t danh y th\u1eddi \u0110\u00f4ng T\u1ea5n, m\u00f4 t\u1ea3 c\u00f3 t\u00e1c d\u1ee5ng ch\u1eefa s\u1ed1t r\u00e9t.<\/p>\n
Trong c\u00e1c ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a D\u1ef1 \u00e1n 523, chi\u1ebft xu\u1ea5t c\u1ee7a thanh hao hoa v\u00e0ng ti\u00eau di\u1ec7t \u0111\u01b0\u1ee3c k\u00fd sinh tr\u00f9ng s\u1ed1t r\u00e9t tr\u00ean chu\u1ed9t, nh\u01b0ng c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u mu\u1ed1n bi\u1ebft nhi\u1ec1u h\u01a1n: ho\u1ea1t ch\u1ea5t n\u00e0o \u0111\u00e3 l\u00e0m \u0111i\u1ec1u n\u00e0y? Trong t\u1ef1 nhi\u00ean, c\u00e2y tr\u1ed3ng n\u00e0o c\u00f3 nhi\u1ec1u ho\u1ea1t ch\u1ea5t \u0111\u00f3 nh\u1ea5t? Li\u1ec7u ho\u1ea1t ch\u1ea5t \u0111\u00f3 c\u00f3 b\u0103ng qua h\u00e0ng r\u00e0o m\u00e1u \u2013 n\u00e3o \u0111\u1ec3 ch\u1eefa tr\u1ecb \u0111\u01b0\u1ee3c b\u1ec7nh s\u1ed1t r\u00e9t th\u1ec3 n\u00e3o? Ho\u1ea1t ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng d\u01b0\u1edbi d\u1ea1ng to\u1ea1 d\u01b0\u1ee3c, thu\u1ed1c u\u1ed1ng v\u00e0 thu\u1ed1c ti\u00eam t\u0129nh m\u1ea1ch hay kh\u00f4ng?<\/p>\n
H\u00e0ng lo\u1ea1t c\u00e2u h\u1ecfi \u0111\u01b0\u1ee3c \u0111\u1eb7t ra, v\u00e0 c\u0169ng nh\u01b0 nhi\u1ec1u ph\u00e1t minh kh\u00e1c, ph\u1ea3i sau 190 l\u1ea7n th\u1ea5t b\u1ea1i, cu\u1ed1i c\u00f9ng nh\u00f3m c\u1ee7a GS Tu Youyou m\u1edbi bi\u1ebft r\u1eb1ng nhi\u1ec7t \u0111\u1ed9 cao \u0111\u00e3 ph\u00e1 hu\u1ef7 c\u00e1c th\u00e0nh ph\u1ea7n trong thanh hao hoa v\u00e0ng, v\u00ec th\u1ebf c\u1ea7n chi\u1ebft xu\u1ea5t v\u1edbi nhi\u1ec7t \u0111\u1ed9 th\u1ea5p. C\u1ea7n n\u00f3i th\u00eam, GS Tu Youyou l\u00e0 ng\u01b0\u1eddi \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ee9ng \u0111\u1ea7u D\u1ef1 \u00e1n 523 v\u00e0o \u0111\u1ea7u n\u0103m 1969.<\/p>\n
Ng\u00e0y 4.10.1971, Tu v\u00e0 c\u1ed9ng s\u1ef1 \u0111\u00e3 chi\u1ebft xu\u1ea5t \u0111\u01b0\u1ee3c m\u1ed9t th\u00e0nh ph\u1ea7n tr\u1ecb s\u1ed1t r\u00e9t c\u00f3 hi\u1ec7u qu\u1ea3 100% tr\u00ean kh\u1ec9 v\u00e0 chu\u1ed9t. Ngay l\u1eadp t\u1ee9c, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111i \u0111\u1ebfn nh\u1eefng v\u00f9ng c\u00f3 d\u1ecbch s\u1ed1t r\u00e9t ho\u00e0nh h\u00e0nh \u1edf Nam Trung Qu\u1ed1c \u0111\u1ec3 th\u1eed<\/p>\n\n\n\n\n
$\"youyou\"$ <\/td>\n<\/tr>\n
Th\u00e1ng 9.2011, GS Tu Youyou (\u1ea3nh) \u0111\u00e3 \u0111\u01b0\u1ee3c qu\u1ef9 Lasker c\u1ee7a M\u1ef9 trao t\u1eb7ng gi\u1ea3i Nghi\u00ean c\u1ee9u y h\u1ecdc l\u00e2m s\u00e0ng Lasker DeBakey. \u0110\u00e2y l\u00e0 m\u1ed9t ph\u1ea7n th\u01b0\u1edfng danh gi\u00e1 \u0111\u01b0\u1ee3c m\u1ec7nh danh gi\u1ea3i \u201cNobel Hoa K\u1ef3\u201d, v\u00ec t\u1eeb ng\u00e0y th\u00e0nh l\u1eadp v\u00e0o n\u0103m 1945 \u0111\u1ebfn nay, 81 ng\u01b0\u1eddi \u0111o\u1ea1t gi\u1ea3i n\u00e0y \u0111\u00e3 gi\u00e0nh gi\u1ea3i Nobel sau \u0111\u00f3, trong \u0111\u00f3 c\u00f3 29 ng\u01b0\u1eddi trong hai th\u1eadp k\u1ef7 qua. Trong l\u1eddi m\u1edf \u0111\u1ea7u b\u00e0i di\u1ec5n v\u0103n ch\u00fac m\u1eebng GS Tu, l\u00fac n\u00e0y \u0111\u00e3 81 tu\u1ed5i, ban t\u1ed5 ch\u1ee9c n\u00f3i: \u201cTrong l\u1ecbch s\u1eed y h\u1ecdc l\u00e2m s\u00e0ng, ch\u00fang ta kh\u00f4ng th\u01b0\u1eddng xuy\u00ean c\u00f3 \u0111\u01b0\u1ee3c m\u1ed9t kh\u00e1m ph\u00e1 \u0111\u00e3 l\u00e0m d\u1ecbu n\u1ed7i \u0111au v\u00e0 tai ho\u1ea1 cho h\u00e0ng tr\u0103m tri\u1ec7u ng\u01b0\u1eddi c\u0169ng nh\u01b0 c\u1ee9u s\u1ed1ng v\u00f4 s\u1ed1 ng\u01b0\u1eddi, \u0111\u1eb7c bi\u1ec7t l\u00e0 tr\u1ebb em, \u1edf h\u01a1n 100 qu\u1ed1c gia\u201d.<\/em><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi. K\u1ebft qu\u1ea3 cho th\u1ea5y ch\u1ea5t n\u00e0y t\u1ed1t h\u01a1n chloroquine r\u1ea5t nhi\u1ec1u. N\u0103m 1972, Tu b\u00e1o c\u00e1o k\u1ebft qu\u1ea3 th\u1eed nghi\u1ec7m trong m\u1ed9t h\u1ed9i ngh\u1ecb qu\u1ed1c gia v\u1ec1 D\u1ef1 \u00e1n 523 v\u00e0 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0 \u0111i \u0111\u00fang h\u01b0\u1edbng. C\u0169ng trong n\u0103m n\u00e0y, nh\u00f3m c\u1ee7a GS Tu nh\u1eadn di\u1ec7n \u0111\u01b0\u1ee3c m\u1ed9t lo\u1ea1i tinh th\u1ec3 kh\u00f4ng m\u00e0u \u0111\u01b0\u1ee3c xem l\u00e0 ho\u1ea1t ch\u1ea5t ch\u00ednh. H\u1ecd g\u1ecdi n\u00f3 l\u00e0 Qinghaosu, ngh\u0129a l\u00e0 \u201cth\u00e0nh ph\u1ea7n c\u01a1 b\u1ea3n c\u1ee7a Qinghao (thanh hao hoa v\u00e0ng)\u201d m\u00e0 ng\u00e0y nay th\u1ebf gi\u1edbi g\u1ecdi l\u00e0 artemisinin.<\/p>\n
Nh\u01b0ng d\u00f9 GS Tu th\u00e0nh c\u00f4ng, m\u1ecdi chuy\u1ec7n c\u0169ng \u0111i v\u00e0o qu\u00ean l\u00e3ng v\u00ec D\u1ef1 \u00e1n 523 l\u00e0 b\u00ed m\u1eadt qu\u1ed1c gia. Artemisinin tinh ch\u1ebf \u0111\u01b0\u1ee3c chuy\u1ec3n \u0111\u1ebfn chi\u1ebfn tr\u01b0\u1eddng Vi\u1ec7t Nam \u0111\u1ec3 h\u1ed7 tr\u1ee3 b\u1ed9 \u0111\u1ed9i Vi\u1ec7t Nam ch\u1ed1ng s\u1ed1t r\u00e9t. M\u1eb7t kh\u00e1c, l\u00fac \u0111\u00f3 t\u1ea1i Trung Qu\u1ed1c v\u1eabn c\u00f2n l\u00e0 th\u1eddi k\u1ef3 C\u00e1ch m\u1ea1ng v\u0103n ho\u00e1 (1966 \u2013 1976), v\u1edbi h\u00e0ng tri\u1ec7u tr\u00ed th\u1ee9c b\u1ecb x\u1eed t\u1ed9i v\u00e0 kh\u00f4ng c\u00f3 m\u1ed9t k\u00eanh ch\u00ednh th\u1ed1ng n\u00e0o \u0111\u1ec3 c\u00f4ng b\u1ed1 nghi\u00ean c\u1ee9u.<\/p>\n
Nh\u01b0ng cho \u0111\u1ebfn nay, ng\u01b0\u1eddi g\u00f3p ph\u1ea7n l\u1edbn nh\u1ea5t cho vi\u1ec7c t\u00ecm ra artemisinin v\u1eabn l\u00e0 m\u1ed9t ch\u1ee7 \u0111\u1ec1 tranh c\u00e3i. Theo Zhiguo Xu v\u00e0 Hepeng Jia, sau khi ngu\u1ed3n tin GS Tu Youyou chi\u1ebft xu\u1ea5t th\u00e0nh c\u00f4ng ho\u1ea1t ch\u1ea5t tr\u1ecb s\u1ed1t r\u00e9t t\u1eeb thanh hao hoa v\u00e0ng lan \u0111i, nhi\u1ec1u nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u1ed9c l\u1eadp kh\u00e1c thu\u1ed9c D\u1ef1 \u00e1n 523 cho bi\u1ebft h\u1ecd c\u0169ng th\u00e0nh c\u00f4ng trong chi\u1ebft xu\u1ea5t ho\u1ea1t ch\u1ea5t theo nh\u1eefng c\u00e1ch kh\u00e1c nhau, th\u1eadm ch\u00ed m\u1ed9t s\u1ed1 ho\u1ea1t ch\u1ea5t c\u00f2n c\u00f3 \u0111\u1ed9 tinh luy\u1ec7n cao h\u01a1n v\u00e0 hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb t\u1ed1t h\u01a1n Qinghaosu. M\u1eb7t kh\u00e1c, vi\u1ec7n Y h\u1ecdc c\u1ed5 truy\u1ec1n Trung Qu\u1ed1c (nay l\u00e0 vi\u1ec7n H\u00e0n l\u00e2m khoa h\u1ecdc y h\u1ecdc Trung Qu\u1ed1c), n\u01a1i GS Tu l\u00e0m vi\u1ec7c, \u0111\u00e3 kh\u00f4ng th\u1ec3 chi\u1ebft xu\u1ea5t \u0111\u1ea1i tr\u00e0 artemisinin. Th\u1ebf nh\u01b0ng theo nh\u00e0 th\u1ea7n kinh h\u1ecdc Rao Yi, khoa tr\u01b0\u1edfng tr\u01b0\u1eddng Khoa h\u1ecdc \u0111\u1eddi s\u1ed1ng thu\u1ed9c \u0111\u1ea1i h\u1ecdc B\u1eafc Kinh v\u00e0 nghi\u00ean c\u1ee9u l\u1ecbch s\u1eed artemisinin trong nhi\u1ec1u n\u0103m, m\u1eb7c d\u00f9 nhi\u1ec1u nh\u00e0 khoa h\u1ecdc c\u0169ng g\u00f3p ph\u1ea7n nh\u1ea5t \u0111\u1ecbnh trong kh\u00e1m ph\u00e1, th\u1ebf nh\u01b0ng c\u00e1ch th\u1ee9c chi\u1ebft xu\u1ea5t ho\u1ea1t ch\u1ea5t m\u00e0 GS Tu \u0111\u1ec1 xu\u1ea5t \u0111\u01b0\u1ee3c xem l\u00e0 b\u01b0\u1edbc ngo\u1eb7t quan tr\u1ecdng trong vi\u1ec7c t\u00ecm ra artemisinin.<\/p>\n
B\u00c0I 2: M\u1ed9t nh\u00e0 khoa h\u1ecdc Anh ki\u00ean c\u01b0\u1eddng<\/h2>\n
SGTT.VN – GS Tu Youyou c\u00f3 c\u00f4ng chi\u1ebft xu\u1ea5t th\u00e0nh c\u00f4ng ho\u1ea1t ch\u1ea5t tr\u1ecb s\u1ed1t r\u00e9t t\u1eeb thanh hao hoa v\u00e0ng. Tuy nhi\u00ean, n\u1ebfu kh\u00f4ng c\u00f3 s\u1ef1 \u0111\u00f3ng g\u00f3p c\u1ee7a c\u1ed9ng \u0111\u1ed3ng khoa h\u1ecdc th\u1ebf gi\u1edbi, n\u1ed5i b\u1eadt l\u00e0 GS Nick White, c\u00f3 l\u1ebd v\u0169 kh\u00ed l\u1ee3i h\u1ea1i \u0111\u1ec3 ng\u0103n ch\u1eb7n th\u1ea3m ho\u1ea1 s\u1ed1t r\u00e9t n\u00e0y ph\u1ea3i m\u1ea5t m\u1ed9t th\u1eddi gian l\u00e2u h\u01a1n m\u1edbi \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ch\u00ednh th\u1ee9c.<\/p>\n
Sinh ra \u0111\u1ec3 nghi\u00ean c\u1ee9u s\u1ed1t r\u00e9t<\/strong><\/p>\n\n\n\n\n
$\"treemchauphi\"$ <\/td>\n<\/tr>\n
H\u1ecdc sinh ch\u00e2u Phi trong ng\u00e0y Ch\u1ed1ng s\u1ed1t r\u00e9t c\u1ee7a ch\u00e2u l\u1ee5c n\u00e0y. \u1ea2nh: TL<\/span><\/em><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
B\u1ee9c x\u00fac v\u00ec s\u1ef1 th\u1edd \u01a1 v\u1edbi nh\u1eefng b\u1eb1ng ch\u1ee9ng r\u00f5 r\u00e0ng v\u1ec1 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb s\u1ed1t r\u00e9t c\u1ee7a artemisinin, GS Nick White \u2013 ng\u01b0\u1eddi g\u1eafn b\u00f3 g\u1ea7n c\u1ea3 \u0111\u1eddi v\u1edbi b\u1ec7nh s\u1ed1t r\u00e9t \u2013 c\u00f3 l\u1ea7n t\u1ef1 h\u1ecfi: \u201cNhi\u1ec1u nh\u00e0 khoa h\u1ecdc \u0111\u00e3 d\u00f9ng ch\u00ednh c\u01a1 th\u1ec3 m\u00ecnh \u0111\u1ec3 th\u1ef1c nghi\u1ec7m, t\u1ea1i sao t\u00f4i kh\u00f4ng l\u00e0m \u0111\u01b0\u1ee3c?\u201d Nick White mu\u1ed1n m\u1eafc b\u1ec7nh s\u1ed1t r\u00e9t r\u1ed3i d\u00f9ng artemisinin t\u1ef1 ch\u1eefa cho m\u00ecnh!<\/p>\n
Ch\u00e0o \u0111\u1eddi \u1edf Anh, sau khi t\u1ed1t nghi\u1ec7p \u0111\u1ea1i h\u1ecdc London ng\u00e0nh d\u01b0\u1ee3c v\u00e0o n\u0103m 1971, Nick White ti\u1ebfp t\u1ee5c nghi\u00ean c\u1ee9u trong c\u00e1c l\u0129nh v\u1ef1c b\u1ec7nh h\u1ecdc, d\u01b0\u1ee3c \u1ee9ng d\u1ee5ng v\u00e0 \u0111i\u1ec1u tr\u1ecb. N\u0103m 1979, c\u01a1 duy\u00ean \u0111\u01b0a \u00f4ng \u0111\u1ebfn Th\u00e1i Lan l\u00e0m vi\u1ec7c cho ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u Y h\u1ecdc nhi\u1ec7t \u0111\u1edbi c\u1ee7a \u0111\u1ea1i h\u1ecdc Oxford. L\u00fac n\u00e0y, \u00f4ng v\u00e0 \u0111\u1ed3ng nghi\u1ec7p t\u00ecnh c\u1edd \u0111\u1ecdc \u0111\u01b0\u1ee3c m\u1ed9t nghi\u00ean c\u1ee9u khoa h\u1ecdc c\u1ee7a Trung Qu\u1ed1c v\u1ec1 thanh hao hoa v\u00e0ng tr\u1ecb s\u1ed1t r\u00e9t. T\u00f2 m\u00f2 v\u1edbi lo\u1ea1i th\u1ea3o d\u01b0\u1ee3c ph\u01b0\u01a1ng \u0110\u00f4ng, \u00f4ng t\u00ecm hi\u1ec3u r\u1ed3i sau \u0111\u00f3 ti\u1ebfn h\u00e0nh nhi\u1ec1u nghi\u00ean c\u1ee9u di\u1ec7n r\u1ed9ng v\u00e0 chi ti\u1ebft tr\u00ean b\u1ec7nh nh\u00e2n. C\u00e0ng nghi\u00ean c\u1ee9u, Nick White v\u00e0 \u0111\u1ed3ng nghi\u1ec7p c\u00e0ng th\u1eeba nh\u1eadn r\u1eb1ng artemisinin hi\u1ec7u qu\u1ea3 h\u01a1n k\u00fd ninh trong \u0111i\u1ec1u tr\u1ecb s\u1ed1t r\u00e9t.<\/p>\n
Tuy nhi\u00ean, artemisinin kh\u00f4ng ph\u1ea3i kh\u00f4ng c\u00f3 nh\u01b0\u1ee3c \u0111i\u1ec3m. Ng\u01b0\u1eddi ta th\u1ea5y r\u1eb1ng n\u1ebfu ch\u1ec9 s\u1eed d\u1ee5ng artemisinin d\u01b0\u1edbi b\u1ea3y ng\u00e0y, nguy c\u01a1 t\u00e1i ph\u00e1t s\u1ed1t r\u00e9t r\u1ea5t cao (50%) v\u00e0 l\u00e2u d\u00e0i c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn l\u1eddn thu\u1ed1c. Gi\u1ea3i ph\u00e1p \u0111\u1eb7t ra l\u00e0 ph\u1ea3i k\u1ebft h\u1ee3p artemisinin v\u1edbi m\u1ed9t lo\u1ea1i thu\u1ed1c kh\u00e1c. Nick White v\u00e0 \u0111\u1ed3ng nghi\u1ec7p \u0111\u00e3 th\u00e0nh c\u00f4ng khi ph\u1ed1i h\u1ee3p artemisinin v\u1edbi mefloquine, trong khi thu\u1ed1c \u0111\u1ea7u t\u00e1c d\u1ee5ng nhanh v\u00e0 \u0111\u00e0o th\u1ea3i nhanh kh\u1ecfi c\u01a1 th\u1ec3 th\u00ec thu\u1ed1c sau t\u00e1c d\u1ee5ng ch\u1eadm, gi\u00fap qu\u00e9t h\u1ebft k\u00fd sinh tr\u00f9ng s\u1ed1t r\u00e9t c\u00f2n l\u1ea1i trong m\u00e1u.<\/p>\n
L\u00e0 gi\u00e1o s\u01b0 y h\u1ecdc nhi\u1ec7t \u0111\u1edbi c\u1ee7a \u0111\u1ea1i h\u1ecdc Mahidol (Th\u00e1i Lan) v\u00e0 \u0111\u1ea1i h\u1ecdc Oxford (Anh), Nick White quan t\u00e2m \u0111\u1ebfn c\u00e1c b\u1ec7nh nhi\u1ec7t \u0111\u1edbi n\u1eb7ng nh\u01b0 th\u01b0\u01a1ng h\u00e0n, s\u1ed1t xu\u1ea5t huy\u1ebft, b\u1ea1ch h\u1ea7u, vi\u00eam m\u00e0ng n\u00e3o, nh\u01b0ng quan t\u00e2m \u0111\u1eb7c bi\u1ec7t nh\u1ea5t c\u1ee7a \u00f4ng v\u1eabn l\u00e0 s\u1ed1t r\u00e9t. \u00d4ng nghi\u00ean c\u1ee9u nhi\u1ec1u v\u1ec1 d\u01b0\u1ee3c l\u00e2m s\u00e0ng c\u00e1c thu\u1ed1c ch\u1ed1ng s\u1ed1t r\u00e9t, sinh l\u00fd b\u1ec7nh v\u00e0 \u0111i\u1ec1u tr\u1ecb s\u1ed1t r\u00e9t th\u1ec3 n\u1eb7ng, s\u1ed1t r\u00e9t \u1edf thai ph\u1ee5. T\u1eeb n\u0103m 1986 \u2013 2001, \u00f4ng tr\u1edf th\u00e0nh gi\u00e1m \u0111\u1ed1c ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u Y h\u1ecdc nhi\u1ec7t \u0111\u1edbi Oxford, ng\u00e0nh Y h\u1ecdc nhi\u1ec7t \u0111\u1edbi, \u0111\u1ea1i h\u1ecdc Mahidol \u2013 Th\u00e1i Lan. N\u0103m 1991, \u00f4ng l\u00e0 m\u1ed9t trong nh\u1eefng ng\u01b0\u1eddi th\u00e0nh l\u1eadp \u0111\u01a1n v\u1ecb nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u1ea1i h\u1ecdc Oxford v\u00e0 Wellcome Trust, n\u1eb1m trong b\u1ec7nh vi\u1ec7n B\u1ec7nh nhi\u1ec7t \u0111\u1edbi TP.HCM. Hi\u1ec7n t\u1ea1i \u00f4ng \u0111\u1ee9ng \u0111\u1ea7u ch\u01b0\u01a1ng tr\u00ecnh nghi\u00ean c\u1ee9u \u0110\u00f4ng Nam \u00c1 c\u1ee7a Wellcome Trust, g\u1ed3m b\u1ed9 ba qu\u1ed1c gia Th\u00e1i Lan, Vi\u1ec7t Nam, L\u00e0o, \u0111\u00f3ng g\u00f3p r\u1ea5t nhi\u1ec1u trong nghi\u00ean c\u1ee9u \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u00f2ng ch\u1ed1ng s\u1ed1t r\u00e9t.<\/p>\n
Chi\u1ebfn \u0111\u1ea5u v\u00ec ng\u01b0\u1eddi ngh\u00e8o<\/strong><\/p>\n
Nick White lu\u00f4n d\u00e0nh m\u1ed9t v\u1ecb tr\u00ed quan tr\u1ecdng cho \u0111\u1ed1i t\u01b0\u1ee3ng ng\u01b0\u1eddi ngh\u00e8o v\u00e0 tr\u1ebb em. Trong m\u1ed9t c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u c\u00f3 t\u00ednh b\u01b0\u1edbc ngo\u1eb7t v\u00e0o n\u0103m 2005, \u00f4ng v\u00e0 c\u1ed9ng s\u1ef1 ch\u1ee9ng minh artesunate \u2013 m\u1ed9t d\u1eabn xu\u1ea5t c\u1ee7a artemisinin \u2013 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u1ef7 l\u1ec7 t\u1eed vong c\u1ee7a s\u1ed1t r\u00e9t th\u1ec3 n\u1eb7ng \u0111\u1ebfn h\u01a1n 1\/3. K\u1ebft qu\u1ea3 ngo\u1ea1n m\u1ee5c n\u00e0y d\u1eabn \u0111\u1ebfn s\u1ef1 thay \u0111\u1ed5i trong ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb cho ng\u01b0\u1eddi l\u1edbn, nh\u01b0ng l\u1ea1i kh\u00f4ng \u0111\u01b0\u1ee3c \u1ee9ng d\u1ee5ng cho tr\u1ebb em, \u0111\u1ed1i t\u01b0\u1ee3ng chi\u1ebfm 1\/5 s\u1ed1 ca t\u1eed vong h\u00e0ng n\u0103m v\u00ec s\u1ed1t r\u00e9t. \u00d4ng l\u1ea1i ti\u1ebfp t\u1ee5c l\u00e0m vi\u1ec7c. Th\u00e1ng 11.2010, c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u c\u1ee7a \u00f4ng \u0111\u0103ng tr\u00ean Lancet cho th\u1ea5y artemisinin c\u0169ng hi\u1ec7u qu\u1ea3 trong vi\u1ec7c gi\u1ea3m t\u1eed vong \u1edf tr\u1ebb em. Trong 5.000 tr\u1ebb em ch\u00e2u Phi b\u1ecb s\u1ed1t r\u00e9t, m\u1ed9t n\u1eeda d\u00f9ng artesunate v\u00e0 m\u1ed9t n\u1eeda d\u00f9ng k\u00fd ninh, k\u1ebft qu\u1ea3 trong nh\u00f3m \u0111\u1ea7u c\u00f3 230 tr\u1ebb t\u1eed vong, c\u00f2n nh\u00f3m sau l\u00e0 297 tr\u1ebb. S\u1ef1 kh\u00e1c nhau \u1edf \u0111\u00e2y l\u00e0 22%, kh\u00f4ng ngo\u1ea1n m\u1ee5c nh\u01b0 \u1edf ng\u01b0\u1eddi l\u1edbn (kh\u00e1c bi\u1ec7t 35%), nh\u01b0ng \u0111i\u1ec1u \u0111\u00e1ng n\u00f3i l\u00e0 tr\u1ebb kh\u00f4ng b\u1ecb h\u00f4n m\u00ea n\u1eb7ng, co gi\u1eadt hay h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft \u0111e do\u1ea1 cu\u1ed9c s\u1ed1ng. Nh\u1edd b\u1eb1ng ch\u1ee9ng n\u00e0y m\u00e0 WHO \u0111\u1ec1 ngh\u1ecb s\u1eed d\u1ee5ng artesunate truy\u1ec1n t\u0129nh m\u1ea1ch nh\u01b0 lo\u1ea1i thu\u1ed1c h\u00e0ng \u0111\u1ea7u trong \u0111i\u1ec1u tr\u1ecb s\u1ed1t r\u00e9t n\u1eb7ng c\u1ee7a tr\u1ebb em.<\/p>\n
…………………………………….<\/p>\n
>> Xem th\u00eam chi ti\u1ebft b\u00e0i vi\u1ebft<\/a><\/p>\n
(Ngu\u1ed3n:di\u1ec5n \u0111\u00e0n)\u00a0<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
Th\u00f4ng th\u01b0\u1eddng ph\u1ea3i \u0111\u1ebfn th\u00e1ng 10 c\u00e1c gi\u1ea3i Nobel m\u1edbi \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1. Tuy nhi\u00ean, t\u1eeb cu\u1ed1i n\u0103m qua \u0111\u00e3 c\u00f3 kh\u00f4ng \u00edt \u0111\u1ed3n \u0111o\u00e1n r\u1eb1ng gi\u1ea3i Nobel Y h\u1ecdc n\u0103m nay s\u1ebd trao cho ng\u01b0\u1eddi c\u00f3 c\u00f4ng t\u00ecm ra artemisinin, lo\u1ea1i thu\u1ed1c ch\u1eefa s\u1ed1t r\u00e9t \u0111\u00e3 c\u1ee9u h\u00e0ng tri\u1ec7u ng\u01b0\u1eddi kh\u1eafp th\u1ebf gi\u1edbi. S\u1ef1 ra \u0111\u1eddi c\u1ee7a lo\u1ea1i thu\u1ed1c n\u00e0y t\u1eeb ng\u00e0y \u0111\u1ea7u ti\u00ean cho \u0111\u1ebfn khi \u0111\u01b0\u1ee3c th\u1ebf gi\u1edbi c\u00f4ng nh\u1eadn l\u00e0 m\u1ed9t c\u00e2u chuy\u1ec7n ly k\u1ef3, v\u00ec b\u1eaft ngu\u1ed3n t\u1eeb cu\u1ed9c chi\u1ebfn ch\u1ed1ng M\u1ef9 c\u1ee7a Vi\u1ec7t Nam v\u00e0 c\u00f3 s\u1ef1 \u0111\u00f3ng g\u00f3p c\u1ee7a gi\u1edbi khoa h\u1ecdc n\u01b0\u1edbc…<\/p>\n","protected":false},"author":2,"featured_media":15955,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[109,95],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/posts\/15950"}],"collection":[{"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/comments?post=15950"}],"version-history":[{"count":1,"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/posts\/15950\/revisions"}],"predecessor-version":[{"id":15954,"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/posts\/15950\/revisions\/15954"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/media\/15955"}],"wp:attachment":[{"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/media?parent=15950"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/categories?post=15950"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pertoo.com\/wp-json\/wp\/v2\/tags?post=15950"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}